Thaum Lub Xya Hli 2024, Pfizer tshaj tawm tias Giroctogenes fitelparvovec tau ua tiav thawj qhov kawg thiab qhov tseem ceeb thib ob kawg hauv Phase III qhov chaw kho mob AFFINE. Thaum Lub Kaum Ob Hlis 2024, Pfizer tau tshaj tawm cov ntaub ntawv ntxaws ntxaws ntawm ASH lub rooj sib tham. Thaum lub Kaum Ib Hlis 2024, Pfizer kuj tau ceeb toom Sangamo tias nws yuav xa daim ntawv teev npe nyob rau thaum ntxov 2025.
Kev cuam tshuam los ntawm cov xov xwm no, Sangamo Therapeutics 'tus nqi Tshuag poob qis los ntawm 60% tom qab kev lag luam, thiab nws cov nqi lag luam tam sim no tsawg dua $ 200 lab.
Giroctogenes fitelparvovec yog ib qho ntawm cov kav dej tseem ceeb ntawm Sangamo Therapeutics.
Sangamo tuaj yeem tau txais kev tswj hwm thiab kev lag luam tseem ceeb ntawm $ 220 lab, nrog rau kev muag khoom ntawm 14-20%, los ntawm Pfizer. Nrog Pfizer txiav tawm kev koom tes, tus nqi lag luam ntawm Giroctogenes fitelparvovec tseem tsis paub meej.
Kev tso tseg cov tshuaj tshiab uas tab tom yuav nkag mus rau theem kev lag luam daws teeb meem feem ntau yog vim muaj kev txhawj xeeb txog nws txoj kev lag luam yav tom ntej.
Nyob rau hauv xyoo tas los no, kev sib tw hauv thaj chaw hemophilia tau dhau los ua nruj heev, nrog FIX / FX bispecific antibodies, TFPI cov tshuaj tiv thaiv, thiab lwm yam tau txais kev pom zoo ib zaug. Qhov yooj yim ntawm kev tswj hwm rau hemophilia tau nce siab heev, thaum qhov kev pom zoo kho noob rau hemophilia A, ROctavian, xws li Biomarin, tau ua tsis zoo, nrog kev muag khoom ntawm $ 7.24 lab hauv peb lub hlis twg thiab kev muag khoom ntawm $ 15.52 lab hauv thawj peb lub hlis twg. Hauv cov ntsiab lus no, nws tsim nyog rau Pfizer tso tseg Girocogene fitelparvovec.
