CAS Nr .: 1809249-37-3 Remdesivir
Lub npe: Remdesivir
CAS Nr .: 1809249-37-3
Cov mis mos molecular: C27H35N6O8P
Molecular Luj: 602.58
EINECS tus lej: 210-629-4
MDL No.: 31657351
Specification:
| Qhov tshwm sim |
Dawb los yog Yuav luag Dawb Hmoov
|
|
Purity (HPLC)
|
>98%
|
Daim ntawv thov:
Remdesivir (GS-5734) yog ib qho nucleoside analogue nrog cov tshuaj tiv thaiv kab mob. Hauv HAE hlwb, nws muaj EC50 tus nqi ntawm 74 nM tiv thaiv SARS CoV thiab MERS CoV, thiab hauv cov hlwb qog hlwb qeeb, nws muaj EC50 tus nqi ntawm 30 nM tawm tsam murine kab mob siab.
| Kev siv | Ib tug prodrug metabolized intracellularly rau lub active triphosphate daim ntawv (GS-443902). Nws inhibits tus kab mob RdRp, ua rau ntxov ntxov txiav ntawm RNA transcription thiab thaiv tus kab mob replication. |
| Smilar cov khoom | Nirmatrelvir/ritonavir (Paxlovid), Casirivimab/imdevimab, Dexamethasone |
| Qhov zoo |
Dav -spectrum kev ua haujlwm tawm tsam tus kabmob coronaviruses Kev pov thawj ua tau zoo hauv kev txo lub sijhawm rov qab los thiab kev tuagGilead Sciences |
Synonyms:
wb 5734
Remdesivir API
Remdesivir (GS-5734)
L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 2-ethylbutyl ester, 6-ester nrog 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile
2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-pheninooxyphosphoryl]
Cim npe nrov: cas 1809249-37-3|Remdesivir, Suav teb cas 1809249-37-3|Remdesivir manufacturers, lwm tus neeg
