CAS Nr .: 1358751-06-0|TSI-653
Lub npe: TAK-653
CAS Nr .: 1358751-06-0
Cov mis mos molecular: C19H23N3O3S
Molecular Luj: 373.47
EINECS tus lej:
MDL Nr.:
Cov ntaub ntawv khoom:
• Zoo li: Dawb rau tawm -dawb crystalline hmoov
• Solubility: Xyaum insoluble hauv dej; soluble nyob rau hauv cov organic solvents
• Kev ruaj ntseg: ruaj khov nyob rau hauv qhuav, txias, thiab tsaus qhov chaw cia; rhiab heev rau cov oxidizing muaj zog
• Purity: Ntau dua lossis sib npaug li 98% (HPLC)
| Kev ua lag luam |
• Cov Lus Qhia Tseem Ceeb: Kev Kho Mob -Txoj Kev Nyuaj Siab (TRD) - Kev Tshawb Fawb Tshiab Tshuaj (IND) theem, tsim los ntawm Takeda & Neurocrine Biosciences • Kev Paub Txog Kev Txawj Ntse: Kev tshawb fawb txog kev txhim kho kev kawm, kev nco, thiab kev mloog zoo nyob rau hauv cov qauv ntawm kev paub tsis meej • Kev Tshawb Fawb Txog Neurological: Cov cuab yeej siv rau kev kawm AMPA receptor physiology, synaptic plasticity, thiab CNS Circuit Court muaj nuj nqi • Kev Tshawb Fawb Txog Kab Mob CNS: Muaj peev xwm siv tau rau hauv schizophrenia thiab Alzheimer's disease (adjunctive research focus) |
| Cov khoom siv hauv qab & siv Case |
• Cov qauv siv & Cov cuab yeej tshawb fawb: Siab-purity TAK-653 (xws li, 5 mg, 100 mg vials) rau hauv vitro/in vivo tshuaj ntsuam xyuas tshuaj • Cov Khoom Siv Kho Mob: Cov khoom siv tshuaj nquag (API) rau Phase II/III sim hauv TRD • Co-Cov qauv (Kev Tshawb Fawb): Ua ke nrog lwm cov kev puas siab puas ntsws los tshawb nrhiav kev ua tau zoo • Assay Cov Khoom Siv: Cov Cheebtsam rau AMPA receptor functional assays (piv txwv li, Ca²⁺ flux hauv hGluA1-qhia xovtooj ntawm tes) |
Synonyms:
TSI-653
Pyrazino[2,1-c][1,2,4]thiadiazine, 9-[4-(cyclohexyloxy)phenyl]-3,4-dihydro-7-methyl-, 2,2-dioxide
TSI 653
NIB-1065845
osavampator
9-(4-(Cyclohexyloxy)Phenyl)-7-Methyl-3,4-Dihydropyrazino[2,1-C][1,2,4]Thidiazine 2,2-Dioxide
Cim npe nrov: cas 1358751-06-0|tak-653, China cas 1358751-06-0|tak-653 manufacturers, lwm tus neeg
