1143532-39-1 capivasertib

Cov Khoom Siv

Tsos tawm-dawb rau daj ntseg beige khoom
Melting taw tes: 161-164 degree
Ntawj 1.381
Cia temp. Lub tub yees
Solubility DMSO (me ntsis), Methanol (me ntsis)

 

Daim Ntawv Thov:

Capivasertib yog ib qho kev nyob rau ntawm tag nrho peb subtypes ntawm serine / Threonine Kinase Akt (AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AKT3) thiab AHIBITS PHOPSRYLATION ntawm DownStrates. Akt ua kom muaj cov qog ua si yog qhov tshwm sim los ntawm ntws los ntawm kev ua kom zoo nkauj, AVENT) kev sib zog ntawm Phosphatidylinositol {}} Kinase (Pik3ca).

Nyob rau hauv vitro, capivasertib txo qhov kev loj hlob ntawm cov kab mob cancer ntawm lub ntsej muag, suav nrog cov uas muaj pik3ca lossis AKT1 kev hloov pauv lossis PTTt 7 hloov. Hauv vivo, capivasertib ib leeg lossis ua ke nrog fluoxetine kev loj hlob qauv nyob rau hauv nas xenotranslantation qauv nrog Pik3ca, AKT1 thiab hloov pauv.

 

Cov lus txhais lus:

capivasertib

1143532-39-1

Azd -5363

Lub truqap

(S) {{0} amino-n - ({}}} hydroxyprropyl) -1- ( 7H-pyrrolo [2, {10}} d] Pyrimidin {{}}} {12}} carboxamide

{{0 {0} amino-n - [(1s) {4 {5 {}} hydroxyprropylropr] {}} (7h-pyrrolo [2, {{{11 d] Pyrimidin {}}}} {13} betboxamide

CC -638

4- piperidinecarboxamide, {{1} amino-n - [(1s}}}}} d] Pyrimidin {13}} yl) -

{{0} amino-n - ({}}}} hydroxyprropyl) -1- (7 H-Pyrrolo (2, {10}} d) Pyrimidin {}}}} {12}} carboxamide

{{0 {0} amino-n - [(1s) {4 {5 {}} hydroxyprropylropr] {}} {7h-pyrrolo [2, {{11 d] Pyrimidin {}}}} piperidine {13} packboxamide

4- piperidinecarboxamide, {{1} Amino-n - ((1s) {}}}}} d) pyrimidin {} {yl) -

capivasertibum

Capivasertib

{{0 {0} amino-n - ((1s) {4 {}} hydroxyprropyl) -1- (7h-pyrrolo (2, 3- d) pyrimidin {}}}}} piperidinecarboxamide

Lub truqap

 

Cim npe nrov: {{0 {0}} Capivasertib, Tuam Tshoj 1143532-39-1} capivasertib manufacturers, cov chaw muag khoom